We examine the repeatability, reliability, and accuracy of differential exoplanet eclipse depth measurements made using the InfraRed Array Camera (IRAC) on the Spitzer Space Telescope during the post-cryogenic mission. We have re-analyzed an existing 4.5{\mu}m dataset, consisting of 10 observations of the XO-3 b system during secondary eclipse, using 7 different techniques for removing correlated noise. We find that, on average, for a given technique the eclipse depth estimate is repeatable from epoch to epoch to within 150 parts per million (ppm). Most techniques derive eclipse depths that do not vary by more than a factor 2 of the photon noise limit. Nearly all methods accurately assess their own errors: for these methods the individual measurement uncertainties are comparable to the scatter in eclipse depths over the 10-epoch sample. To assess the accuracy of the techniques as well as clarify the difference between instrumental and other sources of measurement error, we have also analyzed a simulated dataset of 10 visits to XO-3 b, for which the eclipse depth is known. We find that three of the methods (BLISS mapping, Independent Component Analysis, and Pixel Level Decorrelation) obtain results that are within 2 times the photon limit of the true eclipse depth. When averaged over the 10-epoch ensemble, most of the techniques come within 100 ppm of the true value. Spitzer exoplanet data, if measured following current best practices and reduced using methods such as those described here, can measure repeatable and accurate single eclipse depths, with close to photon-limited results.
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