Spectral distortions of the Cosmic Microwave Background (CMB) offer the possibility of probing processes which occurred during the evolution of our Universe going back up to Z$\simeq 10^7$. Unfortunately all the attempts so far carried out for detecting distortions failed. All of them were based on comparisons among absolute measurements of the CMB temperature at different frequencies. We suggest a different approach: measurements of the frequency derivative of the CMB temperature over large frequency intervals instead of observations of the absolute temperature at few, well separated, frequencies as frequently done in the past. The best observing conditions can be found in space. We discuss therefore the perspectives of new observations in the next years from the ground, at very special sites, and in space as independent missions or as part of other CMB projects
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